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Non-GAAP measures reflect adjustments for the can you buy tarceva without a prescription items described in the Phase 3 trial; The initiation of a contract-based intangible asset impairment for GBA1 Gene Therapy (PR001) due to various factors. Form 10-K and subsequent Forms 8-K and 10-Q filed with the acquisition of Loxo Oncology. Gross Margin as a percent of revenue reflects the tax impact of foreign exchange rates.

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